Consortium Outputs
Publications
Broeckling CD, Beger RD, Cheng LL, Cumeras R, Cuthbertson DJ, Dasari S, Davis WC, Dunn WB, Evans AM, Fernández-Ochoa A, Gika H, Goodacre R, Goodman KD, Gouveia GJ, Hsu P-C, Kirwan JA, Kodra D, Kuligowski J, Lan RS-L, Monge ME, Moussa LW, Nair SG, Reisdorph N, Sherrod SD, Ulmer Holland C, Vuckovic D, Yu L-R, Zhang B, Theodoridis G, Mosley JD. Current practices in LC-MS untargeted metabolomics: a scoping review on the use of pooled quality control samples. Analytical Chemistry. 2023 Dec 6; Online ahead of print. https://doi.org/10.1021/acs.analchem.3c02924
Dunn WB, Kuligowski J, Lewis M, Mosley JD, Schock T, Ulmer Holland C, Zanetti KA, Vuckovic D, on behalf of the metabolomics Quality Assurance and Quality Control Consortium (mQACC). Metabolomics 2022 workshop report: state of QA/QC best practices in LC-MS-based untargeted metabolomics, informed through mQACC community engagement initiatives. Metabolomics. 2023 Nov 8; 19: 93. https://doi.org/10.1007/s11306-023-02060-4
Kirwan JA, Gika H, Beger RD, Bearden D, Dunn WB, Gooodacre R, Theodoridis G, Witting M, Yu L-R, Wilson ID, on behalf of the metabolomics Quality Assurance and Quality Control Consortium (mQACC). Quality assurance and quality control reporting in untargeted metabolic phenotyping: mQACC recommendations for analytical quality management. Metabolomics. 2022 Aug 27; 18: 70. https://doi.org/10.1007/s11306-022-01926-3
Lippa KA, Aristizabal-Henao JJ, Beger RD, Bowden JA, Broeckling C, Beecher C, Davis WC, Dunn WB, Flores R, Goodacre R, Gouveia GJ, Harms AC, Hartung T, Jones CM, Lewis MR, Ntai I, Percy AJ, Raftery D, Schock TB, Sun J, Theodoridis G, Tayyari F, Torta F, Ulmer CZ, Wilson I, Ubhi BK. Reference materials for MS-based untargeted metabolomics and lipidomics: a review by the metabolomics quality assurance and quality control consortium (mQACC). Metabolomics. 2022 Apr 09; 18: 24. https://doi.org/10.1007/s11306-021-01848-6
Evans AM, O’Donovan C, Playdon M, Beecher C, Beger RD, Bowden JA, Broadhurst D, Clish CB, Dasari S, Dunn WB, Griffin JL, Hartung T, Hsu P-C, Huan T, Jans J, Jones CM, Kachman M, Kleensang A, Lewis MR, Monge ME, Mosley JD, Taylor E, Tayyari F, Theodoridis G, Torta F, Ubhi BK, Vuckovic D, on behalf of the Metabolomics Quality Assurance, Quality Control Consortium (mQACC). Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC-MS based untargeted metabolomics practitioners. Metabolomics. 2020 Oct 12; 16(10): 113. https://doi.org/10.1007/s11306-020-01728-5
Beger RD, Dunn WB, Bandukwala A, Bethan B, Broadhurst D, Clish CB, Dasari S, Derr L, Evans A, Fischer S, Flynn T, Hartung T, Herrington D, Higashi R, Hsu P-C, Jones C, Kachman M, Karuso H, Kruppa G, Lippa K, Maruvada P, Mosley J, Ntai I, O'Donovan C, Playdon M, Raftery D, Shaughnessy D, Souza A, Spaeder T, Salholz B, Tayyari F, Ubhi B, Verma M, Walk T, Wilson I, Witkin K, Bearden DW, Zanetti KA. Towards quality assurance and quality control in untargeted metabolomics studies. Metabolomics. 2019 Jan 3; 15(1): 4. https://doi.org/10.1007/s11306-018-1460-7
Meetings
Workshops
Metabolomics 2019 Workshop: The Importance of Quality Assurance and Quality Control in Untargeted Metabolomics, June 24, 2019
Reference Materials for Metabolomics Quality Control [PPTX - 4.06MB] (Christina Jones)
Discussion of QA/QC Practices [PDF - 1.21MB] (Claire O’Donovan, Annie Evans, and mQACC)
Introduction to the Basic Principles of Quality Assurance (QA) and Quality Control (QC) in Untargeted Metabolomics [PPTX - 1.63MB] (Rick Dunn and mQACC)
Metabolomics 2018 Workshop: QA and QC in Untargeted Metabolomics, June 24, 2018
Think Tank on Quality Assurance & Quality Control for Untargeted Metabolomics Studies [PDF - 294 KB] (Krista Zanetti)
Quality Control in Untargeted Metabolomics [PDF - 2.63 MB] (Ping-Ching Hsu, Clary Clish, and Dan Bearden)
Quality Assurance Panel [PDF - 1.13 MB] (Jonathan Mosley, Annie Evans, and Susan Sumner)
Oral Presentations
The Metabolomics Quality Assurance and Quality Control Consortium (mQACC): A Community-led Initiative to Develop and Promote Quality Assurance and Quality Control in Untargeted Metabolomics Research [PDF - 2.29 MB] (Christina Jones, presented at Metabolomics Association of North America Conference, November 16, 2019)
mQACC: A community-led effort to strengthen quality assurance (QA) and quality control (QC) practices in metabolomics research and reporting [PDF - 473 KB] (Jonathon Mosley, presented at Metabolomics 2018)
Poster Presentations
Metabolomics Quality Assurance and quality Control Consortium (mQACC): Reference and Test Material Working Group [PDF - 897 KB] (Christina Jones, presented at Metabolomics 2018)
Quality System Procedures for Untargeted Metabolomics Research [PDF - 275 KB] (Annie Evans and Claire O’Donovan, presented at Metabolomics 2018)
mQACC Outputs and Authorship Guidance
mQACC encourages the collaborative development of outputs that are aligned with the mQACC mission and defined goals of any respective working or task group. Inclusive participation within a defined working or task group should be actively encouraged by the group leads (and/or output leads, if different from the group leads). Authorship should reflect this participation, and be representative of the individual and collaborative intellectual and practical contributions of group members in line with good scientific practice. Where group membership changes during the development of an output, it is up to the group or output lead to arbitrate what constitutes a substantial intellectual or practical contribution. Disputes may be raised to the mQACC coordinating committee for review.
For all mQACC manuscripts the mQACC consortium must be listed as last author as follows: “on behalf of the Metabolomics Quality Assurance and Quality Control Consortium (mQACC)”. Thus, all mQACC members are expected to be given reasonable and defined time (defined by the group/manuscript leads) to review the manuscript and provide feedback to the responsible group prior to journal submission OR approve by default in the absence of feedback. Feedback at this stage alone will not justify named authorship except under exceptional circumstances as determined by the group/manuscript leads. Text must be included in the appropriate section of the publication (e.g., “Author Contributions”) stating that all members of mQACC approved the paper for publication.
Where mQACC members pursue QA/QC-related activities or outputs outside of a working or task group (i.e. independent of the consortium), the resulting material is not subject to the consortium approvals process and must not imply the approval of or affiliation with mQACC.
All new and current mQACC members will be made aware of these authorship guidelines via public dissemination of this policy, to be updated only when the guidance is revised.